Intestinal T-cell function
نویسندگان
چکیده
منابع مشابه
T cell activation alters intestinal structure and function.
Treatment with anti-CD3 antibody (anti-CD3) causes transient diarrhea. In this issue of the JCI, Clayburgh et al. show that, in jejunum of mice injected with anti-CD3 or with TNF, fluid accumulation and changes in epithelial phenotype develop, the latter including an increase in the passive permeability to proteins, smaller solutes, and water and the endocytosis of the brush border Na+/H+ excha...
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Ion channels play a major role in the regulation of T cell function in health and disease. In a computer-based model, established to simulate T cells’ membrane potential (VM) generation, we discovered a discrepancy between the simulation and patch-clamp recordings. The predicted VM was more hyperpolarized than the measured VM, indicating that a yet unknown, depolarizing ion current might ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1982
ISSN: 0016-5085
DOI: 10.1016/0016-5085(82)90164-0